DIVISIÓN DE INVESTIGACIÓN CLÍNICA Y TRASLACIONAL DEL CÁNCER
Assistant Investigator of Clinical and Translational Cancer Research
Co-Director, Human Tissue Engineering Laboratory
Comprehensive Cancer Center, University of Puerto Rico
Assistant Professor, ad honorem
Biochemistry Department, University of Puerto Rico Medical Sciences Campus
Contact: cdiaz@cccupr.edu | carlos.diaz42@upr.edu | (787) 772-8300 ext. 1268
Research
Dr. Díaz Osterman is an Assistant Investigator of Clinical and Translational Cancer Research at the University of Puerto Rico Comprehensive Cancer Center. His work focuses on cancer metabolism, therapy response, cardio-oncology, and the identification of novel multi-omic signatures predictive of outcomes among Puerto Ricans with cancer. Dr. Díaz Osterman has a lifelong passion to contribute to teamwork that improves healthcare throughout the island as well as throughout the Caribbean. His work has been funded by pilot awards from both the Research Centers in Minority Institutions (RCMI) and U54 Partnerships to Advance Cancer Health Equity (PACHE) programs, as well as the Puerto Rico IDeA Network for Biomedical Research Excellence (PR-INBRE) and the Puerto Rico Science, Technology, and Research Trust.
Biography
Dr. Díaz Osterman was awarded his doctoral degree in 2015 from Loma Linda University School of Medicine, after which he conducted his postdoctoral work at Moores Cancer Center at the University of California, San Diego. Following a second postdoctoral training experience at Loma Linda University in the Center for Health Disparities and Molecular Medicine, he returned to Puerto Rico to join the Ponce Research Institute at Ponce Health Sciences University. During his time in Ponce, Dr. Díaz Osterman mentored over 10 trainees and rotational students, whose work resulted in over 30 trainee-led abstracts and several award-winning scientific presentations. He joined the University of Puerto Rico Comprehensive Cancer Center’s Department of Cancer Genetics & Therapeutics in August 2023.
For more information, please visit: https://www.diazostermanlab.org
Selected Publications
Díaz Osterman C.J., Ozmadenci D., Kleinschmidt E.G., Taylor K., Barrie A.M., Jiang S., Bean L., Sulzmaier F., Jean C., Tancioni I., Anderson K., Uryu S., Cordasco E., Li J., Chen X., Fu G., Ojalill M., Rappu P., Heino J., Mark A., Xu G., Fisch K., Kolev V., Weaver D., Pachter J., Gyorffy B., McHale M., Connolly D.C., Molinolo A., Stupack DG., Schlaepfer
D.D. (2019) FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. eLife, 8:e47327. PMID: 31478830.
Kleinschmidt E.G., Miller N.L.G., Ozmadenci D., Tancioni I., Díaz Osterman CJ., Barrie A.M., Taylor K.N., Ye A., Jiang S., Connolly D.C., Stupack D.G., Schlaepfer D.D. (2019) Rgnef promotes ovarian tumor progression and confers protection from oxidative stress. Oncogene, 38(36):6323-6337. PMID: 31308489.
Turay D., Khan S., Díaz Osterman C.J., Curtis M.P., Khaira B., Neidigh J.W., Mirshahidi S., Casiano C.A., Wall N.R. (2016) Proteomic profiling of serum-derived exosomes from ethnically diverse prostate cancer patients. Cancer Investigation, 34(1):1-11. PMID: 26536157.
Recent Meetings & Conferences
2024 ACC Advancing the Cardiovascular Care of the Oncology Patient (Washington, DC)
2023 AACR Special Conference on Prostate Cancer (Denver, CO)
2022 AACR Annual Meeting (New Orleans, LA)