Josué Pérez-Santiago, Ph.D.

Assistant Professor of Computational Biology and Bioinformatics, Division of Cancer Biology, University of Puerto Rico Comprehensive Cancer Center, San Juan, PR.


Complete list of publications:

Dr. Pérez-Santiago received a B.S. in Computer Science and a B.S. in Mathematics from the University of Puerto Rico, Rio Piedras Campus. He obtained his PhD in the Bioinformatics and Systems Biology Program at UCSD, where he investigated the gut microbiome in acute and early HIV infection and its association with the pathogenesis of HIV. In his postdoctoral appointment, he transitioned to NeuroAIDS at the HIV Neurobehavioral Research Center at UCSD investigating genetic factors associated with neuroinflammation and neurocognition. He is currently an Assistant Professor of Bioinformatics and Computational Biology at the University of Puerto Rico Comprehensive Cancer Center. Among his work, he focuses on understanding the role of the human microbiome (gut and oral) in aging-related conditions, such as neurocognitive decline, and cancer in HIV infection with the end-goal of developing microbiome-targeted preventive, diagnostic or treatment strategies for these comorbid conditions. He is also investigating the associations of oral microbiota with oral HPV infection among high-risk Hispanic adults. Current research grants included: (1) Transcriptional Effects and Non-transcriptional Effects of Estrogen in the Pathogenesis of Inflammatory Breast Cancer (NCI, grant number 1R21CA253609-01), and (2) The Oral Microbiome and its Association with Chronic Inflammation and Cancer Risk in HIV+ Adults (RCMI, grant number U54 MD007600).

(Updated: Feb 09, 2021)